金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Progesterone R/NR3C3 Long Name: Progesterone Receptor Aliases: NR3C3; PGR Entrez Gene IDs: 5241 (Human) Background: Progesterone R/NR3C3

The 'B' progesterone receptor (PR-B), or long form, is 933 amino acids (aa) in length. Progesterone receptor-A (PR-A) utilizes a different start site that shortens the N-terminus by 164 amino acids. The N-terminus in both progesterone receptor isoforms is rich in serine that is phosphorylated in response to hormone binding. In the absence of progesterone, few receptor molecules are phosphorylated at Serine 190 (S190). Progesterone increases this number two-fold, providing evidence for hormone stimulation. It has been shown that the two progesterone receptor isoforms can form homodimers as well as heterodimers.