R&D Systems代理PPS032 GABA-A-R beta 3 C-Terminus Affinity Purified Polyclonal Ab (100 UL)-试剂-金山科研平台

R&D Systems代理PPS032 GABA-A-R beta 3 C-Terminus Affinity Purified Polyclonal Ab (100 UL)

2025-06-27

货号：PPS032

品牌：R&D Systems

规格：100UL

目录价：￥5420.00

市场价格：￥4336.00

会员价格：￥4336.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: GABA-A R beta 3 Long Name: gamma-Aminobutyric Acid Type A Receptor, beta-3 Polypeptide Aliases: GABRB3 Entrez Gene IDs: 2562 (Human); 14402 (Mouse); 24922 (Rat) Background: GABA-A-R beta 3

View GABA-A-R beta 3 IHC images. GABA-A-R beta 3 (GABA-A receptor subunit beta 3; also GABR3) is a 53 - 58 kDa member of the ligand-gated ion channel family of proteins. It is generally one of three beta-type subunits that contribute to a GABA-binding pentameric, postsynaptic chloride ion channel on neurons. Alternatively, it can apparently form a homopentameric channel that does not respond to GABA.

Mature human GABA-A-R beta 3 is 448 amino acids (aa) in length. It is a 4-transmembrane glycoprotein that contains an extended N-terminal extracellular region (aa 26 - 245) and a long cytoplasmic loop between aa 328 - 450. There are potential splice variants. One shows an alternate start site at Met65, while others contain either a 48 aa substitution for aa 1 - 228, a nine aa substitution for aa 1 - 80, or a 26 aa substitution for aa 1 - 26. Over aa 26 - 245, human and mouse GABA-A-R beta 3 are absolutely identical in aa sequence.

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