货号：550349

品牌：BD Pharmingen

规格：1EA

目录价：￥3591.00

市场价格：￥2262.33

会员价格：￥1975.05

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with 150 mM NaCl and 0.09% (w/v) sodium azide.

Preparation and Storage

The antibody was purified from tissue culture supernatant by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions. The solution is free of unconjugated antibody. The conjugate should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Usage

This antibody conjugate has been tested by immunofluorescent staining ( 1 mg/million cells) with flow cytometric analysis to assure specificity and reactivity. Mouse Fc Block™ (Cat. no. 553141/553142) should be used when staining with the 6C1 antibody. Since applications vary, each investigator must determine dilutions appropriate for individual use.

Conditions

BD PharMingen will not be responsible for violations or patent infringements which may occur with the use of our products.

Catalog Number

550349

Brand

BD Pharmingen™

Name

PIR-A/B

Concentration

0.2 mg/ml

Size

0.1mg

RegulatoryStatus

RUO

Clone

6C1

Format

PE

Isotype

IgG₁, κ

Immunogen

Recombinant mouse PIR-A1 extracellular domain peptide and the mouse myeloid cell line, WEH13

Strain Host

LEW

Reactivity

QC Testing : Mouse

Applications

Flow cytometry

- Routinely Tested

Clone - References

1. Kubagawa, H., C.-C. Chen, L.H. Ho, T. Shimada, L. Gartland, C. Mashburn, T. Uehara, J.V. Ravetch, and M.D. Cooper. 1999. Biochemical nature and cellular distribution of the paired immunoglobulin-like receptors, PIR-A and PIR-B. J. Exp. Med. 189: 309 - 317.2. Chen, C.-C., V. Hurez, J.S. Brockenbrough, H. Kubagawa, and M.D. Cooper. 1999. Paternal monoallelic expression of the paired immunoglobulin-like receptors PIR-A and PIR-B. Proc. Natl. Acad. Sci. USA 96: 6868 - 6872.3. Kubagawa, H., P.D. Burrows, and M.D. Cooper. 1997. A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Proc. Natl. Acad. Sci. USA 94: 5261 - 5266.4. Maeda, A., M. Kurosaki, and T. Kurosaki. 1998. Paired immunoglobulin-like receptor (PIR)-A is involved in activating mast cells through its association with Fc receptor g chain. J. Exp. Med. 188: 991 - 995.5. Taylor, L.S., and D.W. McVicar. 1999. Functional association of Fc RIg with Arginine⁶³² of paired immunoglobulin-like receptor (PIR)-A3 in murine macrophages. Blood 94: 1790 - 1796.6. Blry, M., H. Kubagawa, C.-C. Chen, F. Vly, M.D. Cooper, and E. Vivier. 1998. The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1. Proc. Natl. Acad. Sci. USA 95: 2446 - 2451.

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