货号：550733

品牌：BD Pharmingen

规格：1EA

目录价：￥5575.00

市场价格：￥3512.25

会员价格：￥3066.25

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Purified immunoglobulin in IHC antibody diluent containing serum* and 0.09% (w/v) sodium azide.

Preparation and Storage

Preparation: The C85-2506 antibody was purified from tissue culture supernatant via Protein A column chromatographyStorage: The antibody should be stored undiluted at 4°C.

Caution

Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Conditions

The information disclosed herein is not to be construed as a recommendation to use the above product in violation of any patents. BD PharMingen will not be held responsible for patent infringement or other violations that may occur with the use of our products.

Catalog Number

550733

Brand

BD Pharmingen™

Name

CD88

Alias

C5a Receptor

Size

1mL

RegulatoryStatus

RUO

Clone

C85-2506

Format

Purified

Isotype

IgG

Reactivity

QC Testing : Human

Applications

Immunohistochemistry-formalin (antigen retrieval required)	- Routinely Tested
Immunohistochemistry-frozen	- Tested During Development

Clone - References

1. Fayyazi, A., Sandau, R., Duong, L. Q., Gotze, O., Radzun, H. J., Schweyer, S., Soruri, A.,& Zwirner, J. 1999. C5a receptor and interleukin-6 are expressed in tissue macrophages and stimulated keratinocytes but not in pulmonary and intestinal epithelial cells. [In Process Citation]. Am. J. Pathol. 154: 495.2. Fureder, W., Agis, H., Willheim, M., Bankl, H. C., Maier, U., Kishi, K., Muller, M. R., Czerwenka, K., Radaszkiewicz, T., Butterfield, J. H., et al. 1995. Differential expression of complement receptors on human basophils and mast cells. Evidence for mast cell heterogeneity and CD88/C5aR expression on skin mast cells. J. Immunol. 155: 3152.3. Gasque, P., Singhrao, S. K., Neal, J. W., Gotze, O., & Morgan, B. P. 1997. Expression of the receptor for complement C5a (CD88) is up-regulated on ractive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system. Am. J. Pathol. 150: 31.4. Morelli, A., A. Larregina, I. Chuluyan, E. Kolkowski, & L. Fainboim. 1996. Expression and modulation of C5a receptor (CD88) on skin dendritic cells. Chemotactic effect of C5a on skin migratory dendritic 5. cells. Immunology. 89:126.6. Nataf, S., N. Davoust & S. R. Barnum. 1998. Kinetics of anaphylatoxin C5a receptor expression during +experimental allergic encephalomyelitis. J. Neuroimmunol. 91:147.7. Paradisis, P. M., I. L. Campbell, and S. R. Barnum. 1998. Elevated complement C5a receptor expression on neurons and glia in astrocyte-targeted interleukin-3 transgenic mice. Glia. 24:338.8. Haviland, D. L., McCoy, R. L., Whitehead, W. T., Akama, H., Molmenti, E. P., Brown, A., Haviland, J. C., Parks, W. C., Perlmutter, D. H., & Wetsel, R. A. 1995. Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung. J. Immunol. 154: 1861.9. Stahel, P. F., K. Frei, H. P. Eugster, A. Fontana, K. M. Hummel, R. A. Wetsel, R. S. Ames, and S. R. Barnum. 1997. TNF-a-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis. J. Immunol. 159:861.10. Wetsel, R. A. 1995. Expression of the complement C5a anaphylatoxin receptor (C5aR) on non-myeloid cells. Immunol Lett. 44:183.11. Spieker-Polet, H., Sethupathi, P., Yam, P. C., & Knight, K. L. 1995. Rabbit monoclonal antibodies: Generating a fusion partner to produce rabbit-rabbit hybridomas. Proc. Natl. Acad. Sci. USA 92: 9348-9352.

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