Spring Bioscience代理

Spring Bioscience，Spring Bioscience代理，BRAF V600E

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Spring Bioscience代理，spring bioscience丝氨酸/苏氨酸蛋白激酶B-RAF（BRAF）是Raf家族的一员。 BRAF突变在良性和恶性肿瘤是常见的。 BRAF改变和突变诱导激活段的构象变化中BRAF V600E突变占绝大多数，导致组成型激酶活性的BRAF的和下游目标连续的磷酸化。已在黑色素瘤，甲状腺乳头状癌，多形性xanthoastrocytomas，朗格汉斯细胞组织细胞增生症，卵巢交界性肿瘤，节细胞胶质瘤，结直肠癌，毛细胞型星形细胞瘤检测到BRAF V600E突变。

Spring Bio,Spring Bio代理,Spring Bioscience

PRODUCT DETAILS:TechnologyMouse MonoclonalClone NameVE1ApplicationIHC-P, WBSpecies ReactivityTestedHuPredicted by homologyIsotypeMouse IgG2aImmunogenSynthetic peptide representing the BRAF V600E mutated amino acid sequence from amino acid 596 to 606 （GLATEKSRWSG）Cellular LocalizationCytoplasmControl TissueColon Carcinoma with BRAF V600E mutationRegulatory RatingResearch Use Only （RUO）Entrez673Storage Requirement2-8°CTarget Molecular Weight95 kDaFormulationRefer to Data SheetCatalog No.VolumeDilutionE192900.1ml50E192920.5ml50E192941.0ml50